We don't have a lot of GMC Sierra 2500 fuel system problems on file — feel free to add yours here. The most common Sierra 2500 fuel system problems cost $5,800 to fix & occur at 131,000 miles. Click on a year below.

Worst Fuel System Problems
high pressure fuel pump failure 2011 GMC Sierra 2500
fuel injectors failed 2004 GMC Sierra 2500
fuel leak 2011 GMC Sierra 2500