We don't have a lot of GMC Sierra 2500 transmission problems on file — feel free to add yours here. The most common Sierra 2500 transmission problems cost $1,900 to fix & occur at 68,000 miles. Click on a year below.

Worst Transmission Problems
shifting problem 2000 GMC Sierra 2500
transmission failure 1999 GMC Sierra 2500
overheating 2016 GMC Sierra 2500