Some 2021 Mustang vehicles equipped with a 5.0L engine and built on or before 11-Feb-2021 may exhibit an intermittent rough running drivability concern with an illuminated malfunction indicator lamp (MIL) and diagnostic trouble codes (DTC) P0351, P0352, P0353 and/or P0354 stored in the powertrain control module (PCM). This may be due to a software parameter within the PCM. To correct the condition, follow the Service Procedure to reprogram the PCM.