The Office of Defects Investigation (ODI) received 1 complaint (NHTSA ID Number 11366557) from a fleet mechanic, who reported in a subsequent interview that he repaired at least 6 subject vehicles that experienced the alleged defect condition. ODI examination of certain EWR field report data further indicates a possible defect trend. The manufacturer published "Service Solution 1034298 - New Cascadia Engine Harness Chafe at A06-95037-000 Bracket" (NHTSA ID Number 10162283) to address the alleged defect condition in May 2019. The manufacturer published "Freightliner Service Bulletin 54-330 Compressor Bracket Modification to Reduce Harness Chafing" (NHTSA ID Number 10177001) to address the alleged defect condition again in June 2020. The manufacturer submitted a "Tech talk discussion on DD harness Chaffe" document (NHTSA ID Number 10182006) to the agency in November 2020, where a mechanic reports the remedy prescribed in Service Bulletin 54-330 may not be effective because it does not adequately address the potential for the engine wiring harness to chafe against the rear mounting bolt for the subject support bracket.A Preliminary Evaluation has been opened to assess the alleged defect.