While waiting behind a vehicle at my place of employment, my front tires were on the top of a speed bump while my back tires were not. When it was my turn to pull up, the vehicle went into neutral on it's own. I pushed the gas and it stayed into neutral. I pushed the brake as well as the button to switch it to drive and it still did not change. On the dash, it was beeping at me to push the brake, then shift. I kept trying that repeatedly, but it would not get out of neutral or shift to any other gear. After spending over a minute on this and cars lining up behind me, I turned the vehicle off which changed it to "park" by default. When I turned it back on, it allowed me to shift into drive and get off the speed bump. I feel this is an important concern Honda should investigate as it's happened to me on 2 occasions.